Amgen Biotech Experience

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The Amgen Biotech Experience (ABE) is an innovative science education programme that introduces secondary and tertiary students to the excitement of scientific discovery. ABE provides secondary and tertiary teachers with the loan of research-grade equipment, supplies, curriculum and professional development.

For more information about the global initiative of the Amgen Biotech Experience, please visit www.amgenbiotechexperience.com

Learn more about Amgen Biotech Experience and how students in Singapore have benefited from the programme.

 

Programme

There are 8 labs involved for students to appreciate the genetic engineering process and its use in biotechnology and drug discovery.

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Teacher Professional Development Workshop

The teacher workshops aim to empower the teachers to bring biotechnology into their classroom.
During the teachers’ workshop, teachers and lab officers will:

  • Understand the ABE curriculum and resources available
  • Learn how to implement the ABE programme in their school
  • Conduct experiments involved in the ABE programme and learn how to teach the Science concepts
  • Learn how to use and maintain the equipment on loan from Science Centre
  • Learn how to prepare the materials required

Upcoming Teacher Workshops

5 November 2019
9am – 6pm
Science Centre Singapore

Labs Covered:

  1. Learn the tools of the trade (Lab 1)
  2. Restriction digest (Lab 2)
  3. Ligation to form recombinant plasmid (Lab 3)
  4. Verification by agarose gel electrophoresis (Lab 4)
  5. Bacteria Transformation (Lab 5)
  6. Protein Purification (Lab 8)

Teachers must attend the ABE Teachers Workshop if they plan to implement ABE on their own in 2020.

To register, please complete the registration form and email to Charissa at Charissa_lin@science.edu.sg by 23 October. For enquiries, please contact Charissa at 6425 2789 or email Charissa_lin@science.edu.sg.

 

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Student Workshops

The student workshops can be implemented by a number of ways:

  1. Teachers will borrow the kits and conduct the programme on their own in school (complimentary)
  2. Science educator from Science Centre will conduct the programme in the school ($9 per lab per pax)
  3. Science educator from Science Centre will conduct the programme at Science Centre ($5 per lab per pax)
  4. Attend a planned ABE programme conducted by a Science Educator (please see below for more information)

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ABE Express

ABE Express are condensed versions of the full ABE curriculum, usually conducted over one to two days. These workshops are conducted in Science Centre Singapore. There are 3 options: ABE Express Beginner, Intermediate and Advance, to cater to different age groups and learning abilities.

ABE Express: Genetic Engineering Beginner

(Sec 1 to Sec 2)
$20 (Inclusive of GST)

1 day
9.30am – 4.00pm (Includes lunch break, food not provided)

Have you wondered how human insulin is produced in the lab? This is done by genetically engineering bacteria to produce insulin. Since its innovation in 1973, genetic engineering has been applied in many fields such as producing genetically modified food, genetic treatments and medicines. Come and learn the basics of Genetic Engineering!

Objectives: 

  1. Learn how genetic engineering can be used to treat genetic diseases such as diabetes.
  2. Learn micropipetting techniques. 
  3. Understand what happens during restriction digest and ligation through a paper activity. 
  4. Understand how DNA is analysed through a technique known as agarose gel electrophoresis.
  5. Conduct a bacteria transformation experiment using the heat shock method.
  6. Learn more about the applications of genetic engineering.

ABE Express: Genetic Engineering Intermediate

(Sec 3 to Sec 5)
$30 (Inclusive of GST)
1.5 days
Day 1: 9.30am to 4.00pm / Day 2: 9.30am to 12.30pm (Includes lunch break, food not provided)

Have you wondered how human insulin is produced in the lab? This is done by genetically engineering bacteria to produce insulin. Since its innovation in 1973, genetic engineering has been applied in many fields such as producing genetically modified food, genetic treatments and medicines. Come and have a first-hand experience of conducting these authentic biotechnological experiments used by researchers around the world!

Objectives:

  1. Define genetic engineering and recombinant DNA cloning. 
  2. Learn micropipetting techniques. 
  3. Perform an experiment on recombinant DNA cloning including digestion of DNA with restriction enzyme, ligation of desired vectors, bacteria transformation, selection for transformed bacteria, agarose gel electrophoresis# and purification of protein product using column chromatography#. 
  4. Learn more about the applications of genetic engineering. 
  5. Explore different perspectives on the effect of genetic engineering. 
    * Also available as a 1-day workshop upon request. Items with # will not be covered for 1-day workshop.

ABE Express: Genetic Engineering Advance

(JC1- JC2/ tertiary level)
$35 (Inclusive of GST)
2 days (Both days are not consecutive)

Day 1: 9.30am to 5pm / Day 2: 9.30am to 4.00pm (Includes lunch break, food not provided)


Have you wondered how human insulin is produced in the lab? This is done by genetically engineering bacteria to produce insulin. Since its innovation in 1973, genetic engineering has been applied in many fields such as producing genetically modified food, genetic treatments and medicines. Come and have a first-hand experience of conducting these authentic biotechnological experiments used by researchers around the world!

Objectives: 

  1. Define genetic engineering and recombinant DNA cloning. 
  2. Learn micropipetting techniques. 
  3. Perform an experiment on recombinant DNA cloning including digestion of DNA with restriction enzyme, ligation of desired vectors, bacteria transformation, selection for transformed bacteria, agarose gel electrophoresis#, purification of protein product using column chromatography# and colony polymerase chain reaction#.
  4. Learn more about the applications of genetic engineering. 
  5. Explore different perspectives on the effect of genetic engineering. 

* Also available as a 1-day workshop upon request. Items with # will not be covered for 1-day workshop.

ABE: Developing a Scientist's Mind

(Secondary level)
5 sessions of 3 hours each (Total 15 hours)

A minimum 1-day gap is required between Sessions 4 and 5. An optional Session 6 is also available upon request to allow students to present their work.


Over the course of history, scientific research has enabled humans to investigate the world around us and solve problems. How do scientists conduct research? Join us as we apply the scientific method in this problem-based learning (PBL) workshop to design and conduct your very own genetic engineering experiment! This workshop can be conducted in Science Centre Singapore or in your school.

Objectives: 

  1. Engage problem-solving skills to investigate a case study. 
  2. Learn molecular biology techniques such as micropipetting*, agarose gel electrophoresis and bacteria transformation.
  3. Learn and apply the scientific method to design an experiment.
  4. Conduct a self-designed laboratory experiment.
  5. Learn to review experimental methodology, analyse results and draw conclusions.   
  6. Explore different perspectives on the effect of genetic engineering.

* Prior knowledge of micropipetting techniques is encouraged but not necessary.

Before attending this workshop, students should have:

  1. Prior understanding of the following:
    1. The structure of DNA and its importance
    2. The relationship between DNA, genes, proteins and traits, or; 
  2. Attended one of the following DNA Lab workshops at Science Centre Singapore:
    1. DNA: Cracking the Code of Life
    2. DNA & Life
    3. Genetic Diseases

New Schools Interested to Join the Programme

For more information, click on the Introduction Guide to find out how to implement this in your school and the Amgen Biotech Experience FAQ.

Contact Details

For enquiries, please email dnalab@science.edu.sg or contact: 

Charissa Lin
Senior Manager, Life Sciences
Tel: 6425 2789
Email: charissa_lin@science.edu.sg